Services

The goal of the CD lab is to perform CD experiments on liquid samples. The CD method is highly accurate, sensitive, reproducible, and non-destructive to the sample.

Equipment:

J-715 JASCO and Peltier system 

Applications: 

• Conformational analysis of biological macromolecules (e.g. proteins)
• Investigating the influence of denaturants, solvents and ligands on conformation and stability of macromolecules
• Monitoring conformational changes under different conditions/thermal stability studies
• Investigating protein-protein interactions as well as interactions/complexation of proteins with various ligands, metals, stabilizers, inhibitors, drugs, etc.
• Studying Interactions/complexation of nucleic acids
• Comparative structure and stability studies of proteins and their mutants
• Distinction of the absolute configuration of optically active compounds and quantitative analysis of enantiomeric mixtures