+30 210 650 3533 openscreen@bio.demokritos.gr

Provided at OPENSCREEN-GR by

  • NCSR “Demokritos” Athens


Circular Dichroism

Circular Dichroism (CD) - NCSR “Demokritos” Athens

The goal of the CD lab is to perform CD experiments on liquid samples. The CD method is highly accurate, sensitive, reproducible, and non-destructive to the sample.


J-715 JASCO and Peltier system 


  • Conformational analysis of biological macromolecules (e.g. proteins)
  • Investigating the influence of denaturants, solvents and ligands on conformation and stability of macromolecules
  • Monitoring conformational changes under different conditions/thermal stability studies
  • Investigating protein-protein interactions as well as interactions/complexation of proteins with various ligands, metals, stabilizers, inhibitors, drugs, etc.
  • Studying Interactions/complexation of nucleic acids
  • Comparative structure and stability studies of proteins and their mutants
  • Distinction of the absolute configuration of optically active compounds and quantitative analysis of enantiomeric mixtures
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